Browsing by Author "Sohrabji, Farida"
Now showing items 1-20 of 39
-
Serpedin, Nesrin (Texas A&M University, 2004-09-30)The leaner mouse carries an autosomal recessive mutation in the α1A subunit of neuronal P/Q-type voltage gated calcium ion channels. Due to this mutation, the leaner mouse exhibits severe ataxia, absence seizures and ...
-
Selvamani, Amutha; Sathyan, Pratheesh; Miranda, Rajesh C.; Sohrabji, Farida; Priller, Josef (PloS One, 2012)
-
Huntington, Taylor Elise (2022-10-20)Parkinson’s disease (PD) is a neurodegenerative disorder primarily characterized by progressive motor dysfunction and currently has no cure. Research has elucidated coalescing molecular dysfunctions including neuroinflammation, ...
-
Roman-Cruz, Glorian M. (2010-07-14)The goal of this study was to identify a sensorimotor behavioral test that predicts infarct volume in animals with ischemic stroke. Stroke is the major cause of behavioral deficits in humans and research on stroke therapies ...
-
Bake, Shameena; Selvamani, Amutha; Cherry, Jessica; Sohrabji, Farida; Arai, Ken (PloS One, 2014)
-
Gunaratna, Ramesh Tharindu (2018-05-01)Female breast cancer (BrCa) is the most common noncutaneous cancer among women in the United States. Human epidemiological studies reveal that p53 codon 72 single nucleotide variants, encoding proline (P72) or arginine ...
-
Effects of Morphine on Activated Microglia and Macrophages in a Rodent Model of Spinal Cord Injury Terminel, Mabel N (2020-07-10)Opioids are among the most effective and commonly prescribed analgesics for the treatment of acute pain after spinal cord injury (SCI). We have shown, however, that morphine administration in the early phase of SCI undermines ...
-
Effects of Morphine on Activated Microglia and Macrophages in a Rodent Model of Spinal Cord Injury Terminel, Mabel N (2020-07-10)Opioids are among the most effective and commonly prescribed analgesics for the treatment of acute pain after spinal cord injury (SCI). We have shown, however, that morphine administration in the early phase of SCI undermines ...
-
Effects of Morphine on Activated Microglia and Macrophages in a Rodent Model of Spinal Cord Injury Terminel, Mabel N (2020-07-10)Opioids are among the most effective and commonly prescribed analgesics for the treatment of acute pain after spinal cord injury (SCI). We have shown, however, that morphine administration in the early phase of SCI undermines ...
-
Sieve, Amy Nicole (Texas A&M University, 2005-02-17)Multiple Sclerosis (MS) is the most common demyelinating condition of the central nervous system (CNS), resulting in paralysis and death. The etiology of MS is unknown. However, genetics, exposure to a pathogen, ...
-
Raymond, Elizabeth S (2016-07-28)Research on long noncoding RNAs (lncRNAs) has increased significantly over the past few decades. However, investigation of lncRNA continues to lag behind that of other noncoding RNAs species like microRNA (miRNA). One ...
-
Consalvo, Kristen M (2022-12-07)During normal inflammation, neutrophils respond to environmental cues to know when to leave a tissue, but the mechanisms behind neutrophil “repulsion” are not well understood. The ability to selectively repel neutrophils ...
-
Gomez, Francisco Pascual (2012-10-19)Multiple sclerosis (MS) is an idiopathic neurodegenerative, demyelinating disease of the central nervous system (CNS). MS affects females more than males (3:1) and pregnancy reduces the number of relapses especially during ...
-
Holgate, Rhonda Renay (2015-04-29)Neurological deficits caused by fetal exposure to ethanol remains prevalent and are recognized as a serious public health issue. The effects of fetal alcohol exposure are multifaceted and is characterized by multiple ...
-
Christensen, Lanette M (2018-04-30)Legionella pneumophila are aqueous environmental bacilli that live within protozoal species and cause a potentially fatal form of pneumonia called Legionnaires’ disease. Not all L. pneumophila strains have the same capacity ...
-
Zarate, Sara Marie (2022-12-10)Parkinson’s disease is a multifaceted neurodegenerative disease characterized by dopamine neuron loss; but more importantly there are no know treatments for PD that can truly alter disease progression. The two major risk ...
-
Johnson, Andre (2019-05-07)Nearly three quarters of all strokes occur in people over 65, and within this older group, strokes are more common and more severe in women than men. Added to this disease burden, is the lack of suitable therapies for ...
-
Vichaya, Elisabeth Good (2012-07-16)A growing body of evidence suggests that social stress contributes to the pathogenesis of neurodegenerative diseases, such as multiple sclerosis (MS). For example, prior research has shown that ...
-
Acca, Gillian M (2017-07-10)Sex differences in stress and anxiety disorders are well reported in the clinical population. For instance, women are twice as likely to be diagnosed with post-traumatic stress disorder (PTSD) compared to men. This difference ...
-
Tsai, Pai Chi (2014-05-05)Maternal alcohol consumption during pregnancy, especially during the first and second trimester, can cause the wide range of severe birth defects classified as fetal alcohol spectrum disorder (FASD). FASD is a wide spectrum ...